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  • In this assay, such symptoms as ataxia, decrease in motor activity and loss ofrighting reflex are observed after intraperitoneal (i.p.) administration in mice of the compound to be tested at doses ranging from 2-1,000 mg/kg body weight.(B) Glass Bead Test (for relief from discomfort associated with irritable bowel syndrome): The glass bead test is carried out with male albino mice of 18-25 grams
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