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  • Discussion Chloroquine (CQ) and hydroxychloroquine (HCQ) have been used for nearly six decades in the treatment and prophylaxis of malaria as well as in the management of systemic lupus erythematosus, rheumatoid arthritis, and other dermatologic and rheumatologic diseases.1 Both medications have an affinity for melanin-rich tissue, including the RPE, and both drugs may affect the metabolism of pho
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