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  • Proinflammatory cytokines, such as IL-1 and TNF-?? which in turn stimulate IL-8, may also stimulate chemokines [22, 34].Table 1: Potential pro- and antitumorigenic roles of cytokines.An interesting example of cytokine-mediated carcinogenesis is human malignant mesothelioma which may be provoked by chronic exposure to asbestos.
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