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  • n).These results indicate that the marker genes are stablyexpressed in differentiated cells in vivo and the possibil-ity of downregulation of fluorescent genes was unlikely,especially in hematopoietic lineages.In this experiment, the resulting chimeric embryosoriginated not only from the injected ES cells but alsofrom the host-derived ICM. Thus, the embryos wouldbe composed of four types of cells:
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