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  • One is a sustained release pharmaceutical preparation (see Japanese Unexamined Patent Publication No. 156617/1985) in which a core is alternately coated with two compositions, namely, with a coating composition comprising a water-soluble polymer such as a polyvinyl alcohol or polyvinylpyrrolidone and a water-insoluble polymer such as ethylcellulose, polyvinyl chloride or Eudragit RS (trade mark, f
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