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  • In this invention, the inactivated pheA, trpR, mtr and tnaAB genes or their DNA fragments contain polynucleotide sequence having sequence homology with the host pheA, trpR, mtr and tnaAB genes, but theses polynucleotide sequences have such mutation as truncation, deletion, substitution, insertion and inversion so as to be incapable of expressing the proteins encoded by pheA, trpR, mtr and tnaAB ge
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