In particular, the present invention provides polypeptides comprising, or alternatively consisting of, the amino acid sequence of residues n-314 of FIGS. 1A and 1B (SEQ ID NO:2), where n is an integer in the range of 2 to 235, and 236 is the position of the first residue from the N-terminus of the complete AIM II polypeptide believed to be required for at least immunogenic activity of the AIM II p