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  • In a particularly preferred embodiment of the invention, the biologically active agent is a pharmaceutically active agent, for example, an isotope. [0075] In one embodiment, the biological effector molecule comprises a nucleic acid selected from the group consisting of an oligonucleotide or modified oligonucleotide, an antisense oligonucleotide or modified antisense oligonucleotide, an aptamer, a
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