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  • Interestingly, although wild-type mice had areduced number of latently infected cells compared to C3???/??? mice, indicating thatcomplement regulates the establishment of ??HV68 latent infection, this effect was notcounteracted by the ??HV68 RCA protein (Kapadia et al., 2002).Poxviruses, such as variola virus, vaccinia virus, monkeypox virus, and ectromelia virus,also encode complement regulatory
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