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  • Bioavailability of insulin was found to be 18% and 5% with 1% of STDHF in rats and rabbits, respectively.[115] The 21-fold increase in nasal bioavailability of human growth hormone with 0.5% STDHF was observed in comparative pharmacokinetic studies in sheep. [116] The nasal bioavailability of protein and peptide molecules such as insulin, calcitonin, human growth hormone, and octreotide using STDH
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