This showed that something had changedSequenced the gyrA gene of some of the bacteria that survived the quinoloneDiscovered that one resistant bacterium had a gyrA genotype that was different from the original colony???s genotype (where the original genotype???s 317th nucleotide was an A, the resistant genotype???s 317th nucleotide was a G); i.e., it is gyrA gene had mutated.Discovered that the gyr