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  • IFN-?? itself stimulates neutrophils to release proinflammatory cytokines such as TNF-??, IL-1??, and KC. Those cytokines together with IFN-?? stimulate the G-cells in the antrum to release the hormone gastrin, but they also inhibit D-cells to express somatostatin, an inhibitor of gastrin-stimulated acid secretion. [7], [40] IL-1?? and TNF-?? are potent inhibitors of parietal cells blocking acid s
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