A prodrug derivative compound of claim 10 wherein the acylated portion of the acylated basic radical has the formula: ##STR247## where R is C1 -C8 alkyl, C2 -C8 alkenyl, aryl, C7 -C12 substituted aryl, and C7 -C12 arylalkyl; and X is a bond, C, O, S, or N.