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  • Proteases are druggable targets, and at present protease inhibitors are now licensed as well as in clinical development to treat different diseases for example osteoporosis, diabetes, cancer, hypertension, and infectious diseases [6???9].Recent advances, including the sequencing of Plasmodium genomes (http://www.plasmodb.org/) and development of new tools for manipulating Plasmodium genes [10], ha
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