While the transmissions of the ventral striatum to the ventral pallidum involve multiple neurotransmitters including Gamma aminobutyric acid (GABA) and substance P, the output of this pathway by way of the ventral pallidum to the thalamus is almost exclusively inhibitory, mediated by GABA. This component is thought to serve as a modulator for the excitatory positive-feedback orbitofrontal thalamic