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  • hetero atom is selected from N, O or S, and wherein l, m, and n are each 0 or 1, provided that l, m, and n are all not zero at the same time.Many of the non-cleavable linkers disclosed herein are described in detail in U.S. Patent publication number 20050169933.Cleavable linkers are linkers that can be cleaved under mild conditions, i.e. conditions under which the activity of the cytotoxic agent
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