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  • The acylation may be effected in aqueous or non-aqueous media and suitable media include an aqueous ketone such as aqueous acetone, an ester e.g. ethyl acetate, or an amide e.g. dimethylacetamide, ora nitrile e.g. acetonitrile, or a halogenated hydrocarbon e.g. methylene dichloride, or mixtures thereof.Acylation with an acid halide may be effected in the presence of an acid binding agent e.g. a te
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