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  • Chemokines are a large family ofchemotactic cytokines that interact with specific G-protein???coupled chemokine receptors.7Chemokines are involved in boththe innate and adaptive immune responses,8and have well-definedroles in cellular movements by providing directional cues andindirectly by enhancing integrin expression and activation.9Inresponse to proinflammatory cytokines such as TNF?, LPS, orI
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