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  • The rate of decline of plasma HIV-1 RNA in the first week of treatment with high-dose valacyclovir is smaller than for a potent reverse transcriptase inhibitor such as tenofovir, where the first-phase viral decay slope is 0.32???0.39 log10 copies per milliliter per day when provided as monotherapy.33 We also found considerable variability among the participants in the decline in plasma HIV-1 RNA a
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