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  • The term ???ameliorates??? or ???amelioration??? as used herein refers to a decrease, reduction or elimination of a condition, disease, disorder, or phenotype, including an abnormality or symptom associated with a disruption in a UBE2G gene. [0034] The term ???abnormality??? refers to any disease, disorder, condition, or phenotype in which a disruption of a UBE2G gene is implicated, including path
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