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  • The proatherogenic bacteria Chlamydia pneumoniae (Cpn) and Aggregatibacter actinomycetemcomitans (Aa) induced pro-inflammatory effects in cultured human peripheral-derived mast cells characterized by the elevated expression and secretion of pro-inflammatory cytokines, including tumor necrosis factor ?? (TNF-??), and chemokines, such as interleukin (IL)-8 and chemokine (C-C motif) ligand 2 (CCL-2).
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