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  • The substrates are reacted with intensive stirring for several hours, preferably from about 0.5 hour to about 24 hours, more preferably from about 1 hour to about 18 hours, most preferably when the reaction is deemed complete and is verified by an analytical technique such as thin layer chromatography (TLC), infrared spectroscopy (IR), proton nuclear magnet resonance (H1 NMR), carbon 13 nuclear ma
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