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  • There is, however, evidence which suggests a genetic predisposition to incidences of acute leukemia. [0895] For example, genetic disorders such as Fanconi anemia and Down syndrome appear to increase risk of acute leukemia, specifically, AML. Evidence supporting a chromosome 21 locus for acute myelogenous leukemia (AML) includes the finding of linkage to 21q22.1-q22.2 in a family with a platelet di
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