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  • The evolutionarily conserved TOR pathway controls many cellular processes, including protein synthesis, ribosome biogenesis, nutrient transport, and autophagy (reviewed in Wullschleger et al., 2006). mTOR assembles into two distinct multiprotein complexes, termed mTORC1 and mTORC2 (Jacinto et al., 2004; Sarbassov et al., 2004). mTORC1 consists of raptor (regulatory associated protein of mTOR), mLS
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