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  • Thus, amide 9! can be produced by reacting compound 6! (where Y is said leaving group except hydroxy), such as an acid halide (e.g. acid chloride, acid bromide, etc.), alkyl ester (e.g. methyl ester, ethyl ester, etc.), active ester (e.g. p-nitrophenyl ester, p-chlorophenyl ester, etc.), imidazolide, or mixed acid anhydride (e.g. mixed acid anhydrides with monoalkyl carbonates, mixed acid anhydrid
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