This finding was observed only in high-risk patients.22 Ho et al.23 demonstrated that concomitant use of clopidogrel and PPIs was associated with an increased risk for recurrent ACS but not for all-cause mortality, while Juurlink et al.19 demonstrated in a population-based nested case???control study that PPIs, except pantoprazole, are associated with re-infarction after treatment for acute myocar