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  • The MC4-R agonist, once past the blood-brain barrier and in the CNS, can then be delivered to various areas of the brain or spinal cord through lymphatic channels, through a perivascular space, or transported through or along neurons. [0044] Use of a neural pathway to transport an MC4-R agonist to the brain, spinal cord or other components of the central nervous system obviates the obstacle presen
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