Thus, in an embodiment, separation can be carried out by applying a separation force of at least about 500 G, for example at least about 1000 G, at least about 2000 G, at least about 3000 G, or at least about 5000 G. Additionally or alternately, separation can be carried out by applying a separation force of not greater than about 16000 G, for example not greater than about 15000 G, not greater th