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  • The dsRNA of the invention comprises an RNA strand (the complementary strand) having a region which is less than 25 nucleotides in length and is complementary to at least a portion of an RNA transcript of an anti-apoptotic target gene, such as Bcl-2, Bcl-w, or Bcl-xL. The use of these dsRNAs enables the targeted degradation of mRNAs of genes that are implicated in uncontrolled cell or tissue growt
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