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  • Theseand other findings suggest a global role for budding yeastORC in the repression of a large number of genes thatrespond to starvation and other stresses.Materials and methodsExpression profiling of orc2-1 cellsStrains employed in these experiments were wild-typeW303-1a (strain GA180); MATa ade2-1 ura3-1 his3-11, 15trp1-1 leu2-3, 112 can1-100, and orc2-1 (strain GA1410);W303-1a, orc2-1), and st
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