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  • The test statistic 2((1nLcase)+(1nLcontrol)???(1nLcombined)) is then chi-squared with r???1 degrees of freedom (where r is the number of haplotypes). [0932] To test for potentially confounding effects or effect-modifiers, such as sex, age, etc., logistic regression can be used with case-control status as the outcome variable, and genotypes and covariates (plus possible interactions) as predictor v
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