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  • The test statistic 2((nLcase)+(lnLcontrol)-(lnLcombined)) is then chi-squared with r-1 degrees of freedom (where r is the number of haplotypes).To test for potentially confounding effects or effect-modifiers, such as sex, age, etc., logistic regression can be used with case-control status as the outcome variable, and genotypes and covariates (plus possible interactions) as predictor variables.Exam
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