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  • Alternatively, a PTM or interacting protein may decrease the calcium concentration required for activation to physiologic levels.PAD4Of all of the PADs, PAD4 is of specific interest because of its importance in innate immunity and its putative role in a variety of pathogenic states, including autoimmune diseases, such as rheumatoid arthritis (RA), multiple sclerosis (MS), ulcerative colitis (UC),
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