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  • Also, it is believed that the mesenchymal stem cells downregulate basophil activation and inhibit cytokines such as TNF-??, chemokines such as Interleukin-8 and monocyte chemoattractant protein, or MCP-1, lipid mediators such as leukotrienes, and inhibit main mediators such as histamine, heparin, chondroitin sulfates, and cathepsin.Allergic diseases or disorders which may be treated include, but a
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