Alkaloids are an important class of active ingredient in herbs/plants, and more than 10,000 alkaloids have been isolated [57], of which more than 80 compounds have been clinically used, including berberine from Coptis chinensis Franch. for bacterial infection and inflammatory disorders [32, 33], ephedrine from Ephedra sinica Stapf. for asthma [58], reserpine from Rauvolfia verticillata (Lour.) Bai