uch as headache, memory and concentration impairments, and muscle and joint pain.2 The symptom complex is not unique for CFS/ME but overlaps with syndromes such as fibromyalgia and irritable bowel syndrome, equally ill defined in terms of pathophysiology.3,4This raises the question of how fatigue is related to other somatic symptoms in adolescents with CFS/ME. Fatigue is not only a symptom of illn