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  • Furthermore, in contrast to proinflammatory cytokines such as TNF-?? and IL-6, which were similarly expressed between wild-type and Trib1-deficient cells in response not only to LPS but also to other TLR ligands, IL-12 p40 was down-regulated in Trib1-deficient cells compared with wild-type cells (Fig. 1 C; Fig. S2, A???C, available at <a href="http://www.jem.org/cgi/content/full/jem.20070183/DC1;">http://www.jem.org/cgi/content/full/jem.20070183/DC1;</a> and Table
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