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  • Several ATP-competitive mTOR inhibitors have been described (Torin1, WYE-125132, PP242, KU-0063794) that inhibit mTOR irrespective of whether it is within mTORC1 or mTORC2 (Growth Factor/Nutrient module in Figures 2 and ???and4;4; Feldman et al, 2009; Garcia-Martinez et al, 2009; Thoreen et al, 2009; Yu et al, 2009; Janes et al, 2010).
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