Celiac disease is an autoimmune disease and it has already been considered for several years now as a genetically determined illness connected to the major histocompatibility complex or HLA. This disease is associated to the existence of class DQ2 and DQ8 HLA antigens. 90-95% of people that suffer from Celiac disease show the haplotype DQ2 and about 5% show the haplotype DQ8.