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  • Lethal toxin is formed from a combination of LF and PA and releases cytokines such as interleukin -1 and tumor necrosis factor (Cieslak, & Eitzen, 1999; Dixon et al, 1999; Ibrahim, et al, 1999; Shafazand et al, 1999).Edema toxin and lethal toxin interfere with host defenses, causing necrosis of lymphatic tissue and the release of high numbers of bacilli into the blood and lymph, which in turn lead
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