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  • Gene linkage studies have provided new insights into epithelial dysfunction in CD. Additionally, innate immune receptors such as Dectin-1 have now been linked to mucosal responses to commensal fungal microorganisms that may play a role in pathobiology of UC.19 The biology of other epithelial cell types, such as Paneth cells, and their roles in intestinal host defense and homeostasis has been illum
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