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  • Because our study focused on designing robust, sensitive probes for gene families, our target sequence set includes virulence gene orthologs found in strains such as E. coli K12 that are avirulent to humans.Table 1Bacterial Strains Used for Probe SelectionWe selected target sequences from the four genomes by searching for virulence-related proteins using 712 sets of profile hidden Markov models (H
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