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  • Neutrophil migration to the pancreas is thought to be initiated mainly by IL-8 early in the course of inflammation.[21, 41] The adhesion of leukocytes to the endothelial wall occurs via expression of ICAM-1 and selectins mediated by IL-8 and other chemokines.[9, 42] ICAM-1 is an inducible molecule normally only expressed at low levels on endothelial surfaces, but expression has been shown to be in
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