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  • We found that all cells with oncogenic KRAS D13 displayed elevated phosphorylation levels of this protein, which were unaffected by treatment with everolimus (Figure 3). p90RSK is an AGC kinase of the RSK family that is phosphorylated and activated by ERK1/2 in response to many growth factors, hormones, and neurotransmitters (22). p90RSK phosphorylates a wide range of substrates, including members
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