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  • AMD, and a risk factor for developing advanced forms of AMD during the next 5 to 10 years [45, 46], that is, GA/AMD or CNV/AMD [47???49].Soft drusen are not only the side effect of dysfunction and degeneration of RPE cells [5, 43, 44, 46], but they indicate also a chronic, pathophysiological parainflammatory process in extracellular matrix.
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