Accessed April 27, 2012. ??? Not adjusted by age or other covariates. ?? An estimated 75% of anti-HCV???positive persons have chronic HCV infection. (Source: Ghany MG, Strader DB, Thomas DL, Seeff LB, American Association for the Study of Liver D. Diagnosis, management, and treatment of hepatitis C: an update. [Practice Guideline.] Hepatology 2009;49(4):1335???74.)