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  • In another embodiment, the antigen-binding polypeptide further comprises a second antibody polypeptide which binds a ligand other than CD40L. In a preferred embodiment, the second antibody polypeptide binds a ligand selected from the group consisting of HSA, TNF??, IL-1, IL-2, IL-4, IL-6, IL-8, IL-12, IL-18, IFN-??, CD2, CD4, CD8, CTLA4, LFA1, LFA3 and VLA4.
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