C1-10 alkyl which may be interrupted by a hetero atom and R5 is C1-10 alkyl, R7 can join with R5 to form a morpholine ring; R8 is H, C1-10 alkyl, or arylalkyl; or when R4 is C1-10 alkyl and R8 is C1-10 alkyl R4 and R8 can join together to form a piperidine ring; R9 is C1-10 alkyl, Y is ???O??? or ???S(O)0-2; Z is a band, ???CO???, or ???SO2???; n is 0; and each R present is independently selected