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  • TGF-??, IL-2, and other signals upregulate FoxP3 expression through induced phosphorylation of SMAD complex and STAT5, whereas IL-6, IL-4 and strong TCR signals downregulate Foxp3 through STAT6, GATA3 and mTOR, respectively.Plasticity of CD4+ FoxP3+ T cellsCurr Opin Immunol. ;21(3):281-285.Publication Types, MeSH Terms, Substances, Grant SupportPublication TypesResearch Support, N.I.H., Extramural
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