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  • . 1993) and display increased resistance to various forms of stress which may be encountered in nature, such as temperature extremes (Lithgow et al. 1994, 1995; Savory et al. 2011) and pathogen infections (Garsin et al. 2003).Loss-of-function mutations in the IIS pathway can lead to life-history trade-offs by inducing developmental arrest in the stress-resistant dauer larval stage in conditions wh
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